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Showing posts with the label deactivation

Just my thoughts #0716

Walt Disney gained worldwide fame with the animated film ‘Steamboat Willie,’ but Disney’s first studio went bankrupt. By the mid-1930s, he had produced over 400 animations, most of which suffered heavy losses. In 1938, Snow White and the Seven Dwarfs made $8 million in just the first half—more than ten times the earnings of other films. Meanwhile, with this animation, the company paid overdue wages to its employees and recovered the losses it had sustained. An unusual event that changes everything is called a “tail event.” 40% of publicly listed companies in the U.S. stock market lose nearly all their market capitalization 10 years after going public. Business and investing, after all, are based on probabilities. No one knows what the “tail event” will be. Therefore, to succeed, you need to try small, steady, many times with little impact, even if you fail. - Joseph’s “just my thoughts”

Just my thoughts #0041

After the Human Genome Project mapped our DNA, we discovered that gene expression and activation patterns can be altered and passed on to future generations without changes in sequence, a phenomenon known as epigenetics. This means that even identical twins, whose genetic information is almost 100% exact, will have different gene activation patterns based on their environment and experiences and pass on their traits to the next generation. A typical phenomenon is methylation (CH3), which is the addition of one carbon and three hydrogens to CpGs in mammalian sequences. Depending on this methylation, although someone inherits the same gene sequence, certain genetic traits can be activated or deactivated. It is also believed that a unique upbringing or education in life influences this phenomenon. Of course, as with any scientific phenomenon or technology, the cause or effect may change over time, but if there's a lesson to be learned, this is one of the most important reasons not to ...